BMS-242 | PD-1/PD-L1 inhibitor | Probechem Biochemicals

Chemical Structure : BMS-242

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货号: PC-70032Not For Human Use, Lab Use Only.

BMS-242 is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 6-100 nM in a homogenous time-resolved fluorescence binding assay.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

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BMS-242 is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 6-100 nM in a homogenous time-resolved fluorescence binding assay.

分子量	449.591
分子式	C28H35NO4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-2-((2,6-dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)amino)-3-methylbutan-1-ol

1. Guzik K, et al. J Med Chem. 2017 Jul 13;60(13):5857-5867.

2. Zak KM, et al. Oncotarget. 2016 May 24;7(21):30323-35.

3. Chupak, L.S., and Zheng, X. Compounds useful as immunomodulators. PCT/US2014/053695, (2015).

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