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首页-小分子抑制剂&激动剂-Immunology/Inflammation-PD-1/PD-L1-BMS-202
BMS-202

Chemical Structure : BMS-202

CAS No.: 1675203-84-5

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BMS-202 (PCC0208025, BMS202, BMS 202, 5J89LIG)

货号: PC-45701Not For Human Use, Lab Use Only.

BMS-202 (PCC0208025) is a small molecule inhibitor of the PD-1/PD-L1 interaction with IC50 of 18 nM in a homogenous time-resolved fluorescence binding assay.

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5 mg ￥980 In stock
10 mg ￥1480 In stock
25 mg ￥2580 In stock
50 mg ￥4280 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BMS-202 (PCC0208025) is a small molecule inhibitor of the PD-1/PD-L1 interaction with IC50 of 18 nM in a homogenous time-resolved fluorescence binding assay.

物理化学性质&存储条件

分子量 419.5161
分子式 C25H29N3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 30 mg/mL
Chemical Name/SMILES

Acetamide, N-[2-[[[2-methoxy-6-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]-3-pyridinyl]methyl]amino]ethyl]-

参考文献

1. Louis S. Chupak, et al. Compounds useful as immunomodulators. WO 2015034820 A1.

2. Guzik K, et al. J Med Chem. 2017 Jul 13;60(13):5857-5867.

3. Zak KM, et al. Structure. 2017 Aug 1;25(8):1163-1174.

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