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首页-小分子抑制剂&激动剂-Immunology/Inflammation-PD-1/PD-L1-BMS-200
BMS-200

Chemical Structure : BMS-200

CAS No.: 1675203-82-3

BMS-200 (BMS200;BMS 200)

货号: PC-70033Not For Human Use, Lab Use Only.

BMS-200 is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 80 nM in a homogenous time-resolved fluorescence binding assay.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    BMS-200 is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 80 nM in a homogenous time-resolved fluorescence binding assay.

    物理化学性质&存储条件

    分子量 499.511
    分子式 C27H27F2NO6
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (S)-4-((4-((3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyl)oxy)-2,5-difluorobenzyl)amino)-3-hydroxybutanoic acid

    参考文献

    1. Guzik K, et al. J Med Chem. 2017 Jul 13;60(13):5857-5867.

    2. Chupak, L.S., and Zheng, X. Compounds useful as immunomodulators. PCT/US2014/053695, (2015).

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