BMS-1001 hydrochloride | PD-1/PD-L1 inhibitor | Probechem Biochemicals

Chemical Structure : BMS-1001 hydrochloride

CAS No.: 2113650-04-5

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BMS-1001 hydrochloride (BMS 1001 HCl, BMS1001 HCl)

货号: PC-70035Not For Human Use, Lab Use Only.

BMS-1001 hydrochloride is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 2.25 nM in a homogenous time-resolved fluorescence binding assay.

规格	价格	库存
5 mg	￥1380	In stock
10 mg	￥2180	In stock
25 mg	￥3780	In stock
50 mg	￥5880	In stock
100 mg		Get quote

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生物&药学活性

BMS-1001 hydrochloride is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 2.25 nM in a homogenous time-resolved fluorescence binding assay.

物理化学性质&存储条件

分子量	667.099
分子式	C35H35ClN2O7HCl
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO (6.67 mg/mL)
Chemical Name/SMILES	(2-((3-cyanobenzyl)oxy)-4-((3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyl)oxy)-5-methylbenzyl)-D-serine hydrochloride

参考文献

1. Guzik K, et al. J Med Chem. 2017 Jul 13;60(13):5857-5867.

2. Chupak, L.S., and Zheng, X. Compounds useful as immunomodulators. PCT/US2014/053695, (2015).

BMS-1001 hydrochloride (BMS 1001 HCl, BMS1001 HCl)

生物&药学活性

物理化学性质&存储条件

参考文献

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BMS-1001 hydrochloride (BMS 1001 HCl, BMS1001 HCl)

生物&药学活性

物理化学性质&存储条件

参考文献

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