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首页-小分子抑制剂&激动剂-TGF-beta/Smad-TGF beta Receptor (TGFBR)-BMP signaling agonist sb4
BMP signaling agonist sb4

Chemical Structure : BMP signaling agonist sb4

CAS No.: 100874-08-6

BMP signaling agonist sb4

货号: PC-35964Not For Human Use, Lab Use Only.

BMP signaling agonist sb4 is a small molecule BMP signaling agonist with EC50 of 73.6 nM, enhances the efficacy of BMPs and activates endogenous BMP4 target genes.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BMP signaling agonist sb4 is a small molecule BMP signaling agonist with EC50 of 73.6 nM, enhances the efficacy of BMPs and activates endogenous BMP4 target genes.
BMP signaling agonist sb4 increases the phosphorylation of key second messengers (SMADs-1/5/9) and also increased expression of direct target genes (inhibitors of DNA binding, ID1 and ID3) in canonical BMP signaling.

物理化学性质&存储条件

分子量 320.204
分子式 C14H10BrNOS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-((4-bromobenzyl)thio)benzo[d]oxazole

参考文献

1. Bradford STJ, et al. J Biol Chem. 2019 Jan 2. pii: jbc.RA118.006817.

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