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BML-210

Chemical Structure : BML-210

CAS No.: 537034-17-6

BML-210 (BML210;BML 210)

货号: PC-45619Not For Human Use, Lab Use Only.

BML-210 is a small molecule histone deacetylase (HDAC) inhibitor that induces Ac-histone in A549 cells with EC50 of 181 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BML-210 is a small molecule histone deacetylase (HDAC) inhibitor that induces Ac-histone in A549 cells with EC50 of 181 uM.
BML-210 inhibits the growth of all cell lines and promotes apoptosis in the human leukemia cell lines (NB4, HL-60, THP-1, and K562).
BML-210 induces growth inhibition and apoptosis and downregulates HDAC1-5 and DAPC complex expression levels in cervical cancer cells.

物理化学性质&存储条件

分子量 339.4314
分子式 C20H25N3O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 30 mg/mL

Chemical Name/SMILES

Octanediamide, N1-(2-aminophenyl)-N8-phenyl-

参考文献

1. Savickiene J, et al. Eur J Pharmacol. 2006 Nov 7;549(1-3):9-18.

2. Wong JC, et al. J Am Chem Soc. 2003 May 14;125(19):5586-7.

3. Borutinskaite VV, et al. Mol Biol Rep. 2012 Dec;39(12):10179-86.

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