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BM212

Chemical Structure : BM212

CAS No.: 146204-42-4

BM212 (BM-212, BM 212)

货号: PC-42236Not For Human Use, Lab Use Only.

BM212 is a novel antitubercular agent that possesses strong inhibitory activity against both Mycobacterium tuberculosis (MIC=0.7-1.5 ug/ml) and some nontuberculosis mycobacteria, inhibits transport activity of MmpL3.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BM212 is a novel antitubercular agent that possesses strong inhibitory activity against both Mycobacterium tuberculosis (MIC=0.7-1.5 ug/ml) and some nontuberculosis mycobacteria, inhibits transport activity of MmpL3.
BM212 also has marked activity against several species of yeasts, including Candida albicans and Cryptococcus neoformans.
BM212 is also highly efficacious against mycobacteria which show resistance to the most common traditional drugs.

物理化学性质&存储条件

分子量 414.3707
分子式 C23H25Cl2N3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Piperazine, 1-[[1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl]methyl]-4-methyl-

参考文献

1. La Rosa V, et al. Antimicrob Agents Chemother. 2012 Jan;56(1):324-31.

2. Deidda D, et al. Antimicrob Agents Chemother. 1998 Nov;42(11):3035-7.

3. Li W, et al. Antimicrob Agents Chemother. 2014 Nov;58(11):6413-23.

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