BLT-1 |CAS:321673-30-7 Probechem Biochemicals

Chemical Structure : BLT-1

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BLT-1 (BLT1)

货号: PC-62034Not For Human Use, Lab Use Only.

BLT-1 is an irreversible Scavenger receptor class B member I (SR-BI) inhibitor that blocks SR-BI-mediated selective lipid uptake and bidirectional cholesterol flux with an IC50 of 50 nM.

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生物&药学活性

BLT-1 is an irreversible Scavenger receptor class B member I (SR-BI) inhibitor that blocks SR-BI-mediated selective lipid uptake and bidirectional cholesterol flux with an IC50 of 50 nM; significantly inhibits baicalin-induced cholesterol efflux in THP-1 macrophages.

物理化学性质&存储条件

分子量	241.397
分子式	C12H23N3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Hexyl-1-cyclopentanone thiosemicarbazone

参考文献

1. Yu M, et al. Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12243-8.

2. Nieland TJ, et al. J Lipid Res. 2007 Aug;48(8):1832-45. Epub 2007 May 28.

3. Yu R, et al. Exp Ther Med. 2016 Dec;12(6):4113-4120.

BLT-1 (BLT1)

生物&药学活性

物理化学性质&存储条件

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BLT-1 (BLT1)

生物&药学活性

物理化学性质&存储条件

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