BLI-489 | CAS 635322-76-8 Probechem Biochemicals

Chemical Structure : BLI-489

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BLI-489 (BLI 489)

货号: PC-38335Not For Human Use, Lab Use Only.

BLI-489 is a bicyclic penem inhibitor that inhibits class A, C, and D beta-lactamases with synergistic effects with piperacillin.

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生物&药学活性

BLI-489 is a bicyclic penem inhibitor that inhibits class A, C, and D beta-lactamases with synergistic effects with piperacillin.
The combination of piperacillin-BLI-489 demonstrated improved activity compared to that of piperacillin-tazobactam against the problematic extended-spectrum beta-lactamase- and AmpC-expressing strains.

物理化学性质&存储条件

分子量	305.31
分子式	C13H11N3O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R,Z)-6-((5,6-dihydro-8H-imidazo[2,1-c][1,4]oxazin-2-yl)methylene)-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

参考文献

1. Peter J Petersen, et al. Antimicrob Agents Chemother. 2009 Feb;53(2):370-84.

2. Petersen PJ, et al. Antimicrob Agents Chemother. 2009 Apr;53(4):1698-700.

3. Wang YC, et al. J Antimicrob Chemother. 2021 Jan 19;76(2):451-459.

BLI-489 (BLI 489)

生物&药学活性

物理化学性质&存储条件

参考文献

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BLI-489 (BLI 489)

生物&药学活性

物理化学性质&存储条件

参考文献

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