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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-AMPK-BL-AD008
BL-AD008

Chemical Structure : BL-AD008

CAS No.: 2660985-19-1

BL-AD008 (BL-AD 008)

货号: PC-35642Not For Human Use, Lab Use Only.

BL-AD008 (BL-AD 008) is a novel small molecule, dual-target activator targeting AMPK/ZIPK.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    BL-AD008 (BL-AD 008) is a novel small molecule, dual-target activator targeting AMPK/ZIPK.
    BL-AD008 demonstrates remarkable anti-proliferative activities toward cervical cancer cells and could induce apoptosis by death-receptor and mitochondrial pathways.
    BL-AD008 also shows anti-tumor activities and induces apoptosis by targeting AMPK/ZIPK in vivo.

    物理化学性质&存储条件

    分子量 501.045
    分子式 C28H25ClN4OS
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (Z)-5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-3-benzylidene-6-chloroindolin-2-one

    参考文献

    1. Fu L, et al. Oncotarget. 2015 Apr 10;6(10):8071-88.

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