BL-1020 |CAS:503537-33-5 Probechem Biochemicals

Chemical Structure : BL-1020

加入收藏

BL-1020 (BL1020, BL 1020)

货号: PC-63550Not For Human Use, Lab Use Only.

BL-1020 is an ester of GABA and perphenazine, fuctions as orally-active antipsychotic agent and acts as a D2 antagonist and GABA agonist.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

BL-1020 is an ester of GABA and perphenazine, fuctions as orally-active antipsychotic agent and acts as a D2 antagonist and GABA agonist.
BL-1020 reduces dopamine activity and enhances GABAA activity, shows pro-cognitive effects and potential for the treatment of schizophrenia.
BL-1020 displays strong dopamine and serotonin (5HT) receptor inhibition ((D2LK(iz)=0.066 nM, D(2S)Ki=0.062 nM, 5-HT2A Ki=0.21 nM).

物理化学性质&存储条件

分子量	525.533
分子式	C25H34Cl2N4O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-[4-[3-(2-chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethyl 4-aminobutanoate hydrochloride

参考文献

1. Geffen Y, et al. Eur Neuropsychopharmacol. 2009 Jan;19(1):1-13.

2. Nudelman A, et al. J Med Chem. 2008 May 8;51(9):2858-62.

3. Appel L, et al. Eur Neuropsychopharmacol. 2009 Dec;19(12):841-50.

4. Geffen Y, et al. J Clin Psychiatry. 2012 Sep;73(9):e1168-74.

BL-1020 (BL1020, BL 1020)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

BL-1020 (BL1020, BL 1020)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.