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首页-小分子抑制剂&激动剂-Others-Amyloids-BIOD303
BIOD303

Chemical Structure : BIOD303

CAS No.: 91271-78-2

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BIOD303 (BIOD 303;BIOD303)

货号: PC-60873Not For Human Use, Lab Use Only.

BIOD303 is a novel conformational modulator of α-synuclein with EC50 of 105 uM, potentially outcompetes spermine in binding to α-synuclein.

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25 mg ￥1280 In stock
50 mg ￥1880 In stock
100 mg ￥3180 In stock
250 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BIOD303 is a novel conformational modulator of α-synuclein with EC50 of 105 uM, potentially outcompetes spermine in binding to α-synuclein.
BIOD303 binds to monomeric α-synuclein in vitro and significantly reduces α-synuclein aggregation in a neuronal cell culture model.

物理化学性质&存储条件

分子量 190.29
分子式 C12H18N2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(3-(pyrrolidin-1-ylmethyl)phenyl)methanamine

参考文献

1. Moree B, et al. J Biol Chem. 2015 Nov 13;290(46):27582-93.

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