BIO1211 |CAS:187735-94-0 Probechem Biochemicals

Chemical Structure : BIO1211

CAS No.: 187735-94-0

加入收藏

BIO1211 (BIO-1211;BIO 1211)

货号: PC-35546Not For Human Use, Lab Use Only.

BIO1211 (BIO-1211) is a potent, highly specific integrin α4β1 (VLA-4) inhibitor with Kd/IC50 of 20 pM/4 nM for the activated form of α4β1.

规格	价格	库存
5 mg	￥3280	In stock
10 mg	￥5280	In stock
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

BIO1211 (BIO-1211) is a potent, highly specific integrin α4β1 (VLA-4) inhibitor with Kd/IC50 of 20 pM/4 nM for the activated form of α4β1.
BIO1211 displays >200-fold selectivity over a range of other integrins (IC50 >100 uM for α1β1, α5β1 and α6β1), and reacts only with activated VLA4。
BIO1211 inhibits ovalbumin-induced lung inflammation in vivo.

物理化学性质&存储条件

分子量	708.813
分子式	C36H48N6O9
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	L-Proline, N-[[4-[[[(2-methylphenyl)amino]carbonyl]amino]phenyl]acetyl]-L-leucyl-L-a-aspartyl-L-valyl- (9CI)

参考文献

1. Chen LL, et al. J Biol Chem. 1999 May 7;274(19):13167-75.

2. Chen LL, et al. J Biol Chem. 2001 Sep 28;276(39):36520-9.

3. Koo GC, et al. Am J Respir Crit Care Med. 2003 May 15;167(10):1400-9.

4. Karanam BV, et al. Xenobiotica. 2007 May;37(5):487-502.

BIO1211 (BIO-1211;BIO 1211)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

BIO1211 (BIO-1211;BIO 1211)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.