BILH-434 |CAS:760169-28-6 Probechem Biochemicals

Chemical Structure : BILH-434

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BILH-434 (BILH434)

货号: PC-62478Not For Human Use, Lab Use Only.

BILH-434 is a potent HPV11 E1/E2/DNA complex inhibitor that binds to the transactivation domain (TAD) of E2 protein with a Kd of 40 nM, has an IC50 of 180 nM in the E1-E2-ori complex formation assay..

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生物&药学活性

BILH-434 is a potent HPV11 E1/E2/DNA complex inhibitor that binds to the transactivation domain (TAD) of E2 protein with a Kd of 40 nM, has an IC50 of 180 nM in the E1-E2-ori complex formation assay.

物理化学性质&存储条件

分子量	608.446
分子式	C29H19Cl2N3O6S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2R,3'R,4'S,5'R)-5'-(3,4-dichlorophenyl)-5-methyl-1,3-dioxo-4'-[[4-(thiadiazol-4-yl)phenyl]carbamoyl]spiro[indene-2,2'-oxolane]-3'-carboxylic acid

参考文献

1. Arkin MR, et al. Chem Biol. 2014 Sep 18;21(9):1102-14.

2. Wang Y, et al. J Biol Chem. 2004 Feb 20;279(8):6976-85.

BILH-434 (BILH434)

生物&药学活性

物理化学性质&存储条件

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BILH-434 (BILH434)

生物&药学活性

物理化学性质&存储条件

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