BI Compound D | RSV L-protein polymerase inhibitor | Probechem Biochemicals

Chemical Structure : BI Compound D

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BI Compound D (RSV L-protein inhibitor)

货号: PC-60361Not For Human Use, Lab Use Only.

BI Compound D is a potent non-nucleoside RSV L-protein polymerase inhibitor with IC50 of 89 nM.

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生物&药学活性

BI Compound D is a potent non-nucleoside RSV L-protein polymerase inhibitor with IC50 of 89 nM.
BI Compound D shows anti-RSV activity with IC50 of 57.6 nM and 47.8 nM for RSV A2 and RSV B-EST, respectively.
BI Compound D shows weak cytotoxicity (CC50=600 nM).

物理化学性质&存储条件

分子量	600.68
分子式	C32H36N6O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-Amino-8-(3-((3,4-dimethoxyphenethyl)amino)propyl)-6,6-dimethyl-2-(4-methyl-3-nitrophenyl)-1H-imidazo[4,5-h]isoquinoline-7,9(6H,8H)-dione

参考文献

1. Liuzzi M, et al. J Virol. 2005 Oct;79(20):13105-15.

2. Mason SW, et al. Nucleic Acids Res. 2004 Sep 8;32(16):4758-67.

3. Coates M, et al. Antimicrob Agents Chemother. 2017 Jun 26. pii: AAC.00737-17.

BI Compound D (RSV L-protein inhibitor)

生物&药学活性

物理化学性质&存储条件

参考文献

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BI Compound D (RSV L-protein inhibitor)

生物&药学活性

物理化学性质&存储条件

参考文献

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