Chemical Structure : BIBS-39
CAS No.: 133085-33-3
货号: PC-45692Not For Human Use, Lab Use Only.
BIBS-39 (BIBS 39) is a selective nonpeptide angiotensin II receptor antagonist with Ki of 29 nM and 480 nM for AT1 and AT2 respectively.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥1280 | In stock | |
10 mg | ¥1980 | In stock | |
25 mg | ¥3580 | In stock | |
50 mg | Get quote | ||
100 mg | Get quote |
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BIBS-39 (BIBS 39) is a selective nonpeptide angiotensin II receptor antagonist with Ki of 29 nM and 480 nM for AT1 and AT2 respectively.
BIBS-39 shows no high affinity for other receptors, shifts the AII concentration-contractile response curves in isolated rabbit aorta with pA2 of 8.14 and a slope of 1.06.
BIBS-39 shows effective antihypertensives in the model of the renal hypertensive rat.
分子量 | 524.6533 | |
分子式 | C32H36N4O3 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
DMSO: ≥ 32 mg/mL |
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Chemical Name/SMILES |
[1,1'-Biphenyl]-2-carboxylic acid, 4'-[[2-butyl-6-[[(cyclohexylamino)carbonyl]amino]-1H-benzimidazol-1-yl]methyl]- |
1. Zhang J, et al. Eur J Pharmacol. 1992 Jul 21;218(1):35-41.
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