BI 7189 |CAS:1883429-32-0 Probechem Biochemicals

Chemical Structure : BI 7189

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BI 7189 (BI7189, BI-7189)

货号: PC-62271Not For Human Use, Lab Use Only.

BI 7189 is a highly selective bromodomains of BRD9 and BRD7 inhibitor with IC50<50 nM for BRD9, displays >1,000 fold selectivity over the bromodomains of BRD4.

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生物&药学活性

BI 7189 is a highly selective bromodomains of BRD9 and BRD7 inhibitor with IC50<50 nM for BRD9, displays >1,000 fold selectivity over the bromodomains of BRD4.
BI 7189 suppresses the proliferation of AML cells.

物理化学性质&存储条件

分子量	330.428
分子式	C19H26N2O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-[4-[(dimethylamino)methyl]-3,5-dimethoxyphenyl]-1,3,6-trimethylpyridin-2-one

参考文献

1. Hohmann AF, et al. Nat Chem Biol. 2016 Sep;12(9):672-9.

2. Pérez-Salvia M, et al. Epigenetics. 2017 May 4;12(5):323-339.

BI 7189 (BI7189, BI-7189)

生物&药学活性

物理化学性质&存储条件

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BI 7189 (BI7189, BI-7189)

生物&药学活性

物理化学性质&存储条件

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