BI 703704 | sGC activator | Probechem Biochemicals

Chemical Structure : BI 703704

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BI 703704 (BI-703704;BI703704)

货号: PC-60643Not For Human Use, Lab Use Only.

BI 703704 is a potent soluble guanylate cyclase (sGC) activator, reduces progression of renal damage in the ZSF1 rat, shows the potential as an effective therapy for diabetic nephropathy.

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生物&药学活性

BI 703704 is a potent soluble guanylate cyclase (sGC) activator, reduces progression of renal damage in the ZSF1 rat, shows the potential as an effective therapy for diabetic nephropathy.

物理化学性质&存储条件

分子量	559.725
分子式	C32H37N3O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(1R,5S,8s)-3-(4-(5-methyl-2-((2-methyl-4-(piperidine-1-carbonyl)benzyl)oxy)phenyl)thiazol-2-yl)-3-azabicyclo[3.2.1]octane-8-carboxylic acid

参考文献

1. Boustany-Kari CM, et al. J Pharmacol Exp Ther. 2016 Mar;356(3):712-9.

2. Stasch JP, et al. Curr Opin Pharmacol. 2015 Apr;21:95-104.

BI 703704 (BI-703704;BI703704)

生物&药学活性

物理化学性质&存储条件

参考文献

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BI 703704 (BI-703704;BI703704)

生物&药学活性

物理化学性质&存储条件

参考文献

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