BI-4732 | EGFR inhibitor | Probechem Biochemicals

Chemical Structure : BI-4732

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货号: PC-21761Not For Human Use, Lab Use Only.

BI-4732 is a potent, highly BBB penetrant, fourth-generation EGFR inhibitor against EGFR activating mutations, including C797S.

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BI-4732 is a potent, highly BBB penetrant, fourth-generation EGFR inhibitor against EGFR activating mutations, including C797S.

分子量	592.69
分子式	C32H36N10O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(1R,4R)-5-[2-[(8aR)-Hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl]-6-[6-(4-methoxy-3-pyridinyl)-4-methyl-1H-pyrazolo[4,3-c]pyridin-1-yl]-1-methyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-oxa-5-azabicyclo[2.2.1]heptane

1. Eun Ji Lee, et al. Clin Cancer Res. 2024 Feb 8. doi: 10.1158/1078-0432.CCR-23-2951.