Chemical Structure : BI-3812
CAS No.: 2166387-64-8
货号: PC-60950Not For Human Use, Lab Use Only.
BI-3812 is a highly potent and efficacious BCL6 inhibitor that potently inhibits the interaction of the BTB/POZ domain of BCL6 with several co-repressors in vitro with IC50 of <3 nM.
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---|---|---|---|
5 mg | ¥2680 | In stock | |
10 mg | ¥4280 | In stock | |
25 mg | ¥7280 | In stock | |
50 mg | Get quote | ||
100 mg | Get quote |
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BI-3812 is a highly potent and efficacious BCL6 inhibitor that potently inhibits the interaction of the BTB/POZ domain of BCL6 with several co-repressors in vitro with IC50 of <3 nM.
BI-3812 inhibits the BCL6/Co-repressor complex formation with IC50 of 40 nM in vitro.
分子量 | 558.036 | |
分子式 | C26H32ClN7O5 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
1-(5-chloro-4-((8-methoxy-1-methyl-3-(2-(methylamino)-2-oxoethoxy)-2-oxo-1,2-dihydroquinolin-6-yl)amino)pyrimidin-2-yl)-N,N-dimethylpiperidine-4-carboxamide |
1. Kerres N, et al. Cell Rep. 2017 Sep 19;20(12):2860-2875.
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