BI-2545 |CAS:2162961-71-7 Probechem Biochemicals

Chemical Structure : BI-2545

CAS No.: 2162961-71-7

加入收藏

BI-2545 (BI2545;BI 2545)

货号: PC-60142Not For Human Use, Lab Use Only.

BI-2545 is a novel potent, selective, orally available Autotaxin inhibitor with IC50 of 2.1 and 3.4 nM for huamn and rat ATX, respectively.

规格	价格	库存
5 mg	￥980	In stock
10 mg	￥1480	In stock
25 mg	￥2580	In stock
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

BI-2545 is a novel potent, selective, orally available Autotaxin inhibitor with IC50 of 2.1 and 3.4 nM for huamn and rat ATX, respectively.
BI-2545 displays good potency in the LPA and rat whole blood assay (IC50=29 nM).
BI-2545 shows substantial lowering of LPA in vivo, and excellent PK/Target Engagement relationship.

物理化学性质&存储条件

分子量	527.427
分子式	C23H19F6N5O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3,5-bis(trifluoromethyl)benzyl (1R,5S,6r)-6-((1H-benzo[d][1,2,3]triazole-5-carboxamido)methyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate

参考文献

1. Christian A. Kuttruff, et al. ACS Med. Chem. Lett., 2017, 8 (12), pp 1252-1257. DOI: 10.1021/acsmedchemlett.7b00312

BI-2545 (BI2545;BI 2545)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

BI-2545 (BI2545;BI 2545)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.