BI-1935 |CAS:940954-41-6 Probechem Biochemicals

Chemical Structure : BI-1935

CAS No.: 940954-41-6

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BI-1935 (BI1935)

货号: PC-63248Not For Human Use, Lab Use Only.

BI-1935 is a potent, selective small molecule inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 7 nM.

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5 mg	￥2280	In stock
10 mg	￥3680	In stock
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生物&药学活性

BI-1935 is a potent, selective small molecule inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 7 nM.
BI-1935 is also highly active in a cellular Hep G2-DHET assay format with IC50 of <1 nM.
BI-1935 can also be used in vivo and showed a dose dependent effect on mean arterial pressure blood pressure in Dahl salt sensitive rats.
BI-1935 also shows good selectivity against hCYP epoxygenases 2J2/2C9/2C19 and IL-2.

物理化学性质&存储条件

分子量	498.466
分子式	C24H21F3N6O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(2-ethoxyethyl)-6-oxo-N-(5-(3-(pyridin-3-yl)-5-(trifluoromethyl)-1H-pyrazol-1-yl)pyridin-2-yl)-1,6-dihydropyridine-3-carboxamide

参考文献

1. Patent WO2007067836A2.

BI-1935 (BI1935)

生物&药学活性

物理化学性质&存储条件

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BI-1935 (BI1935)

生物&药学活性

物理化学性质&存储条件

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