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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Protein Phosphatase/PTP-BI-0314
BI-0314

Chemical Structure : BI-0314

CAS No.: 2244560-46-9

BI-0314 (BI0314;BI 0314)

货号: PC-35665Not For Human Use, Lab Use Only.

BI-0314 (BI0314) is an allosteric activator of protein tyrosine phosphatase non-receptor type 5 (PTPN5, STEP) with potency of 56% at 500 uM, displays no activity against hPTP1B and hTCPTP..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    BI-0314 (BI0314) is an allosteric activator of protein tyrosine phosphatase non-receptor type 5 (PTPN5, STEP) with potency of 56% at 500 uM, displays no activity against hPTP1B and hTCPTP.

    物理化学性质&存储条件

    分子量 286.302
    分子式 C13H17F3N4
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    1-(3-(piperidin-4-yl)-5-(trifluoromethyl)phenyl)guanidine

    参考文献

    1. Tautermann CS, et al. J Med Chem. 2018 Sep 12. doi: 10.1021/acs.jmedchem.8b00857.

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