BI-0252 |Cas:1818291-27-8 Buy BI-0252 from ProbeChem, Global Biochemicals Supplier

Chemical Structure : BI-0252

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BI-0252 (BI 0252;BI0252)

货号: PC-60301Not For Human Use, Lab Use Only.

BI-0252 is a potent, highly selective, orally active MDM2-p53 interaction inhibitor with IC50 of 4 nM.

规格	价格	库存	数量
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250 mg		Get quote

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生物&药学活性

BI-0252 is a potent, highly selective, orally active MDM2-p53 interaction inhibitor with IC50 of 4 nM.
BI-0252 shows in vivo efficacy in a SJSA-1 xenograft model.

物理化学性质&存储条件

分子量	566.45
分子式	C30H26Cl2FN3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-[(3S,3'S,3'aS,5'R,6'aS)-6-chloro-3'-(3-chloro-2-fluorophenyl)-1'-(cyclopropylmethyl)-2-oxo-1,2,3',3'a,4',5',6',6'a-octahydro-1'H-spiro[indole-3,2'-pyrrolo[3,2-b]pyrrole]-5'-yl]benzoic acid

参考文献

1. Gollner A, et al. J Med Chem. 2016 Nov 23;59(22):10147-10162.

BI-0252 (BI 0252;BI0252)

生物&药学活性

物理化学性质&存储条件

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BI-0252 (BI 0252;BI0252)

生物&药学活性

物理化学性质&存储条件

参考文献

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