BF844 (BioFocus 844)

Chemical Structure : BF844

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货号: PC-62222Not For Human Use, Lab Use Only.

BF844 (BioFocus 844) is a small molecules capable of stabilizing mutant USH3 mutation CLRN1(N48K).

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

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生物&药学活性

BF844 (BioFocus 844) is a small molecules capable of stabilizing mutant USH3 mutation CLRN1(N48K).
BF844 effectively attenuated progressive hearing loss and prevented deafness in mouse model potentially prevents both sensory deficiencies in patients with USH3.

物理化学性质&存储条件

分子量	378.85
分子式	C21H19ClN4O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-chloro-3,5-diphenyl-1H-pyrazolo[3,4-c]pyridazin-1-yl)-2-methylpropan-2-ol

参考文献

1. Alagramam KN, et al. Nat Chem Biol. 2016 Jun;12(6):444-51.