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首页-小分子抑制剂&激动剂-Epigenetics-Bromodomain-BETi-211
BETi-211

Chemical Structure : BETi-211

CAS No.: 1995867-02-1

BETi-211 (BETi 211;BETi211)

货号: PC-60932Not For Human Use, Lab Use Only.

BETi-211 is a novel potent small-molecule BET bromodomain (BRD) inhibitor that binds to BET proteins with Ki values of <1 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

BETi-211 is a novel potent small-molecule BET bromodomain (BRD) inhibitor that binds to BET proteins with Ki values of <1 nM.
BETi-211 exhibits >10-100 times more potent than RX-37, JQ-1, OTX-015 or IBET-762.

物理化学性质&存储条件

分子量 487.564
分子式 C26H29N7O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(3-cyclopropyl-1-ethyl-1H-pyrazol-5-yl)-7-(3,5-dimethylisoxazol-4-yl)-6-methoxy-2-(methoxymethyl)-9H-pyrimido[4,5-b]indol-4-amine

参考文献

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