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首页-小分子抑制剂&激动剂-Apoptosis-Bcl-2-BDM49234
BDM49234

Chemical Structure : BDM49234

CAS No.: 618405-72-4

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BDM49234 (BDM 49234)

货号: PC-20242Not For Human Use, Lab Use Only.

BDM49234 is a selective small molecule inhibitor of anti-apoptotic protein BCL2A1/Bfl-1 with IC50 of 6.3 uM (inhibition FITC–Bim BH3 binding to Bfl-1).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    BDM49234 is a selective small molecule inhibitor of anti-apoptotic protein BCL2A1/Bfl-1 with IC50 of 6.3 uM (inhibition FITC–Bim BH3 binding to Bfl-1).

    物理化学性质&存储条件

    分子量 359.49
    分子式 C22H21N3S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-((2-methyl-1H-indol-3-yl)(4-(methylthio)phenyl)methyl)pyridin-2-amine

    参考文献

    1. Anne-Laure Mathieu, et al. J Biomol Screen. 2014 Aug;19(7):1035-46.

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