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首页-小分子抑制剂&激动剂-Apoptosis-Bcl-2-BDM44898
BDM44898

Chemical Structure : BDM44898

CAS No.: 340220-68-0

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BDM44898 (BDM 44898)

货号: PC-20241Not For Human Use, Lab Use Only.

BDM44898 is a small molecule inhibitor of anti-apoptotic protein BCL2A1/Bfl-1 with IC50 of 1.6 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    BDM44898 is a small molecule inhibitor of anti-apoptotic protein BCL2A1/Bfl-1 with IC50 of 1.6 uM.
    BDM44898 exerted proapoptotic effect on BP3 and IM9 cell line in propidium iodide/ Annexin V double staining and flow cytometry, as well as delayed the growth of lymphoid tumor in immunocompromised mice.

    物理化学性质&存储条件

    分子量 413.29
    分子式 C19H13BrN2O2S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (E)-1-(3-bromophenyl)-5-((E)-3-phenylallylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione

    参考文献

    1. Patent WO2016079067A1.

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