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首页-小分子抑制剂&激动剂-Others-Other Targets-BDM43124
BDM43124

Chemical Structure : BDM43124

CAS No.: 1333227-75-0

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BDM43124

货号: PC-26431Not For Human Use, Lab Use Only.

BDM43124 is the methyl ester precursor of BDM43079, which is a selective inhibitor of insulin degrading enzyme (IDE) with IC50 of 0.1 uM, inhibits the hydrolysis of amyloid-β1-40 by IDE in in SH-SY5Y cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

BDM43124 is the methyl ester precursor of BDM43079, which is a selective inhibitor of insulin degrading enzyme (IDE) with IC50 of 0.1 uM, inhibits the hydrolysis of amyloid-β1-40 by IDE in in SH-SY5Y cells.

物理化学性质&存储条件

分子量 415.49
分子式 C21H29N5O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

((((S)-2-(1H-Imidazol-4-yl)-1-methylcarbamoyl-ethylcarbamoyl)-methyl)-(3-phenyl-propyl)-amino)-acetic acid methyl ester

参考文献

1. Julie Charton, et al. Eur J Med Chem. 2015 Jan 27:90:547-67.

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