BDK inhibitor BT3 | BDK inhibitor | Probechem Biochemicals

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Chemical Structure : BDK inhibitor BT3

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BDK inhibitor BT3 (BT3)

货号: PC-49379Not For Human Use, Lab Use Only.

BDK inhibitor BT3 is a small molecule allosteric inhibitor of BCKDC kinase (BDK).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BDK inhibitor BT3 is a small molecule allosteric inhibitor of BCKDC kinase (BDK, branched-chain ketoacid dehydrogenase kinase).
BT3 significantly increase BCKDC activity in wild-type and MSUD cells.
BT3 is a prodrug of BT2 is more efficient than BT2 itself in enhancing BCKDC activity at the cellular level.

物理化学性质&存储条件

分子量	371.192
分子式	C13H8Cl2N4O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-acetamido-1,2,5-oxadiazol-3-yl)-3,6-dichlorobenzo[b]thiophene-2-carboxamide

参考文献

1. Shih-Chia Tso, et al. J Biol Chem. 2014 Jul 25;289(30):20583-93.

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BDK inhibitor BT3 (BT3)

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BDK inhibitor BT3 (BT3)

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