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BCL6-IN-13

Chemical Structure : BCL6-IN-13

CAS No.: 2230407-20-0

BCL6-IN-13 (BCL6 ligand-1)

货号: PC-28688Not For Human Use, Lab Use Only.

BCL6-IN-13 (BCL6 ligand-1) is a high affinity small molecule ligand and inhibitor of BCL-6, inhibits BCL6 with IC50 of 2 nM, is usefull for PROTAC design.

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5 mg ¥2180 In stock
10 mg ¥3580 In stock
25 mg ¥5580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BCL6-IN-13 (BCL6 ligand-1) is a high affinity small molecule ligand and inhibitor of BCL-6, inhibits BCL6 with IC50 of 2 nM, is usefull for PROTAC design.

物理化学性质&存储条件

分子量 530.97
分子式 C24H27ClN6O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(5-Chloro-4-((8-methoxy-1-methyl-3-(2-(methylamino)-2-oxoethoxy)-2-oxo-1,2-dihydroquinolin-6-yl)amino)pyrimidin-2-yl)piperidine-4-carboxylic acid

参考文献

1. Steffen Steurer, et al. New 6-amino-quinolinone compounds and derivatives as bcl6 inhibitors. WO2018108704.

2. Shunatona HP, et al. J Med Chem. 2025 Oct 23;68(20):21502-21519.

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