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BCI-137

Chemical Structure : BCI-137

CAS No.: 112170-24-8

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BCI-137 (BCI137)

货号: PC-62379Not For Human Use, Lab Use Only.

BCI-137 is a chemical compound able to compete with Argonaute 2 miRNAs binding, binds to Ago2 with Kd of 126 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    BCI-137 is a chemical compound able to compete with Argonaute 2 miRNAs binding, binds to Ago2 with Kd of 126 uM.
    BCI-137  displaces Ago2 from the miR-155 host gene promoter paralleling an increase in histone H4 acetylation, favors RA-induced differentiation of the APL cell line NB4.

    物理化学性质&存储条件

    分子量 313.284
    分子式 C11H11N3O6S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-(2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamido)propanoic acid

    参考文献

    1. Masciarelli S, et al. ACS Chem Biol. 2014 Aug 15;9(8):1674-9.

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