Chemical Structure : BCI-137
CAS No.: 112170-24-8
货号: PC-62379Not For Human Use, Lab Use Only.
BCI-137 is a chemical compound able to compete with Argonaute 2 (Ago2) miRNAs binding, binds to Ago2 with Kd of 126 uM.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 mg | ¥780 | In stock | |
| 10 mg | ¥1180 | In stock | |
| 25 mg | ¥1980 | In stock | |
| 50 mg | ¥2980 | In stock | |
| 100 mg | Get quote |
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BCI-137 is a chemical compound able to compete with Argonaute 2 (Ago2) miRNAs binding, binds to Ago2 with Kd of 126 uM.
BCI-137 displaces Ago2 from the miR-155 host gene promoter paralleling an increase in histone H4 acetylation, favors RA-induced differentiation of the APL cell line NB4.
| 分子量 | 313.284 | |
| 分子式 | C11H11N3O6S | |
| 外观性状 | Solid | |
| 储存条件 |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-(2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamido)propanoic acid |
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1. Masciarelli S, et al. ACS Chem Biol. 2014 Aug 15;9(8):1674-9.
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