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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Phosphodiesterase (PDE)-BC8-15C
BC8-15C

Chemical Structure : BC8-15C

CAS No.: 901263-25-0

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BC8-15C

货号: PC-23481Not For Human Use, Lab Use Only.

BC8-15C is a potent, selective PDE11A inhibitor with IC50 of 0.08 uM in in vitro enzyme assays, also inhibits PDE4A with IC50 of 0.13 uM, shows little to no activity against PDE1, PDE2, PDE3, PDE5, PDE9, PDE10.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

BC8-15C is a potent, selective PDE11A inhibitor with IC50 of 0.08 uM in in vitro enzyme assays, also inhibits PDE4A with IC50 of 0.13 uM, shows little to no activity against PDE1, PDE2, PDE3, PDE5, PDE9, PDE10.

物理化学性质&存储条件

分子量 303.37
分子式 C18H17N5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-ethyl-N-(m-tolyl)-[1,2,4]triazolo[4,3-c]quinazolin-5-amine

参考文献

1. Demirbas D, et al. PLoS One. 2013 Aug 14;8(8):e71279.

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