BC8-15

Chemical Structure : BC8-15

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货号: PC-23480Not For Human Use, Lab Use Only.

BC8-15 is a small molecule inhibitor of PDE4 and PDE8 with IC50 of 0.28 uM (PDE4A) and 0.22 uM (PDE8A), also displays significant activity against PDE10A and PDE11A (IC50=1.2-1.6 uM).

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生物&药学活性

BC8-15 is a small molecule inhibitor of PDE4 and PDE8 with IC50 of 0.28 uM (PDE4A) and 0.22 uM (PDE8A), also displays significant activity against PDE10A and PDE11A (IC50=1.2-1.6 uM).
BC8-15 shows weak activity against PDEs from the PDE1, PDE2, PDE3, PDE5, PDE9, PDE10.
BC8-15 elevates steroidogenesis in mouse Leydig cells as a single pharmacological agent.

物理化学性质&存储条件

分子量	333.35
分子式	C18H15N5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-((3-ethyl-[1,2,4]triazolo[4,3-c]quinazolin-5-yl)amino)benzoic acid

参考文献

1. Demirbas D, et al. PLoS One. 2013 Aug 14;8(8):e71279.

BC8-15

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物理化学性质&存储条件

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BC8-15

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物理化学性质&存储条件

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