BC11-38

Chemical Structure : BC11-38

CAS No.: 686770-80-9

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货号: PC-23482Not For Human Use, Lab Use Only.

BC11-38 is a potent and selective PDE11 inhibitor with IC50 of 0.28 uM, without acitivity against PDE1-10.

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5 mg	￥780	In stock
10 mg	￥1180	In stock
25 mg	￥1980	In stock
50 mg	￥2980	In stock
100 mg		Get quote

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生物&药学活性

BC11-38 is a potent and selective PDE11 inhibitor with IC50 of 0.28 uM, without acitivity against PDE1-10.
BC11-38 significantly increases cAMP levels and cortisol production in H295R cells, both in the absence and presence of the adenylate cyclase activator forskolin.
BC11-38 effect is not observed in HeLa cells that have low PDE11 activity.

物理化学性质&存储条件

分子量	304.43
分子式	C15H16N2OS2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-Phenyl-2-(propylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one

参考文献

1. Ceyhan O, et al. Chem Biol. 2012 Jan 27;19(1):155-63.

BC11-38

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BC11-38

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