BAY85-8501 |CAS:1161921-82-9 Probechem Biochemicals

Chemical Structure : BAY85-8501

CAS No.: 1161921-82-9

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BAY85-8501 (BAY 85-8501;BAY 858501)

货号: PC-60474Not For Human Use, Lab Use Only.

BAY 85-8501 (BAY85-8501) is a potent, selective human neutrophil elastase (HNE) inhibitor with IC50 of 65 pM.

规格	价格	库存
2 mg	￥2280	In stock
5 mg	￥3580	In stock
10 mg	￥5480	In stock
25 mg		Get quote
100 mg		Get quote

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生物&药学活性

BAY 85-8501 (BAY85-8501) is a potent, selective human neutrophil elastase (HNE) inhibitor with IC50 of 65 pM.
BAY 85-8501 displays no significant inhibition toward 21 related serine proteases (>30 uM).
BAY 85-8501 demonstrates completely prevented the development of lung injury and subsequent inflammation in vivo.

物理化学性质&存储条件

分子量	474.458
分子式	C22H17F3N4O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-4-(4-cyano-2-(methylsulfonyl)phenyl)-3,6-dimethyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydropyrimidine-5-carbonitrile

参考文献

1. von Nussbaum F, et al. ChemMedChem. 2015 Jul;10(7):1163-73.

2. von Nussbaum F, et al. ChemMedChem. 2016 Jan 19;11(2):199-206.

BAY85-8501 (BAY 85-8501;BAY 858501)

生物&药学活性

物理化学性质&存储条件

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BAY85-8501 (BAY 85-8501;BAY 858501)

生物&药学活性

物理化学性质&存储条件

参考文献

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