BAY 60-2770 |CAS:1027642-43-8 Probechem Biochemicals

Chemical Structure : BAY 60-2770

CAS No.: 1027642-43-8

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BAY 60-2770 (BAY 602770, BAY60-2770)

货号: PC-63047Not For Human Use, Lab Use Only.

BAY 60-2770 is an NO-independent activator of sGC (soluble guanylyl cyclase) with EC50 of 5.4 nM.

规格	价格	库存
5 mg	￥1280	In stock
10 mg	￥1980	In stock
25 mg	￥3480	In stock
50 mg	￥5580	In stock
100 mg		Get quote

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生物&药学活性

BAY 60-2770 is an NO-independent activator of sGC (soluble guanylyl cyclase) with EC50 of 5.4 nM.
BAY 60-2770 demonstrates vasodilator activity in the pulmonary and systemic vascular beds that is enhanced by ODQ and NOS inhibition.

物理化学性质&存储条件

分子量	623.645
分子式	C35H33F4NO5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-({(4-Carboxybutyl)[2-(5-fluoro-2-{[4'-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]amino}methyl)benzoic acid

参考文献

1. Pankey EA, et al. Am J Physiol Heart Circ Physiol. 2011 Mar;300(3):H792-802.

2. Knorr A, et al. Arzneimittelforschung. 2008;58(2):71-80.

3. Jones AW, et al. J Pharmacol Exp Ther. 2010 Oct;335(1):85-91.

4. Mendes-Silverio CB, et al. PLoS One. 2012;7(11):e47223.

BAY 60-2770 (BAY 602770, BAY60-2770)

生物&药学活性

物理化学性质&存储条件

参考文献

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BAY 60-2770 (BAY 602770, BAY60-2770)

生物&药学活性

物理化学性质&存储条件

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