BAY 41-8543 |CAS:256498-66-5 Probechem Biochemicals

Chemical Structure : BAY 41-8543

CAS No.: 256498-66-5

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BAY 41-8543 (BAY418543, BAY41-8543)

货号: PC-63048Not For Human Use, Lab Use Only.

BAY 41-8543 is an NO-independent sGC (soluble guanylyl cyclase) stimulator, inhibits collagen-mediated aggregation in washed human platelets (IC50=90 nM).

规格	价格	库存
5 mg	￥1280	In stock
10 mg	￥1980	In stock
25 mg	￥3480	In stock
50 mg	￥5480	In stock
100 mg		Get quote

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生物&药学活性

BAY 41-8543 is an NO-independent sGC (soluble guanylyl cyclase) stimulator, inhibits collagen-mediated aggregation in washed human platelets (IC50=90 nM).
BAY 418543 is a potent direct stimulator of the cyclic GMP/PKG/VASP pathway in platelets and synergizes with NO over a wide range of concentrations.

物理化学性质&存储条件

分子量	420.452
分子式	C21H21FN8O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(4-morpholinyl)-4,6-pyrimidinediamine

参考文献

1. Stasch JP, et al. Br J Pharmacol. 2002 Jan;135(2):333-43.

2. Stasch JP, et al. Br J Pharmacol. 2002 Jan;135(2):344-55.

3. Amirjanians M, et al. Oncotarget. 2017 May 2;8(18):29613-29624.

BAY 41-8543 (BAY418543, BAY41-8543)

生物&药学活性

物理化学性质&存储条件

参考文献

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BAY 41-8543 (BAY418543, BAY41-8543)

生物&药学活性

物理化学性质&存储条件

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