BAY38-7271 | CB1/CB2 agonist | Probechem Biochemicals

Chemical Structure : BAY38-7271

加入收藏

BAY38-7271 (BAY 38-7271)

货号: PC-21983Not For Human Use, Lab Use Only.

BAY 38-7271 is selective, highly potent and cannabinoid CB1/CB2 receptor agonist with 0.46-1.85 nM for rat brain, human cortex, or recombinant human CB1 receptors.

规格	价格	库存	数量
25 mg		Get quote
100 mg		Get quote
200 mg		Get quote
1 g		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

BAY 38-7271 is selective, highly potent and cannabinoid CB1/CB2 receptor agonist with 0.46-1.85 nM for rat brain, human cortex, or recombinant human CB1 receptors.
BAY 38-7271 shows high affinity to cannabinoid CB2 receptors (Ki=6 nM, recombinant human cannabinoid CB2 receptor).
BAY 38-7271 induced a dose-dependent reduction in body temperature (minimal effective dose = 6 μg/kg, i.v.) in rat hypothermia assays.
BAY 38-7271 demonstrated highly potent and efficient neuroprotective properties in rat traumatic brain injury model.
BAY 38-7271 shows pronounced neuroprotective properties that do not result from drug-induced hypothermia, devoid of typical cannabinoid-like side effects.

物理化学性质&存储条件

分子量	430.44
分子式	C20H21F3O5S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-[[(2R)-2,3-Dihydro-2-(hydroxymethyl)-1H-inden-4-yl]oxy]phenyl 4,4,4-trifluoro-1-butanesulfonate

参考文献

1. Mauler F, et al. BAY 38-7271: a novel highly selective and highly potent cannabinoid receptor agonist for the treatment of traumatic brain injury. CNS Drug Rev. 2003 Winter;9(4):343-58.

2. Mauler F, et al. J Pharmacol Exp Ther. 2002 Jul;302(1):359-68.

3. De Vry J, et al. Eur J Pharmacol. 2002 Dec 20;457(2-3):147-52.

BAY38-7271 (BAY 38-7271)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

BAY38-7271 (BAY 38-7271)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.