BAY 2965501 | DGK zeta inhibitor | Probechem Biochemicals

Chemical Structure : BAY 2965501

CAS No.: 2732902-08-6

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BAY 2965501 (BAY2965501)

货号: PC-20666Not For Human Use, Lab Use Only.

BAY2965501 is a potent selective inhibitor of diacylglycerol kinases zeta (DGKζ), restores T-cell cellular DAG level and induces pERK activation in anergic T-cells via DGK inhibition to assist T-cell mediate tumor cell kill.

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5 mg	￥3980	In stock
10 mg	￥5980	In stock
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100 mg		Get quote

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生物&药学活性

BAY2965501 is a potent selective inhibitor of diacylglycerol kinases zeta (DGKζ), restores T-cell cellular DAG level and induces pERK activation in anergic T-cells via DGK inhibition to assist T-cell mediate tumor cell kill.

物理化学性质&存储条件

分子量	414.46
分子式	C20H19FN4O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	NC([C@@H](C)N(C1=CC=C(C=C1)F)C2=NC(N)=C(C(C3=CC=C(C=C3)OC)=O)S2)=O

参考文献

1. Nicole Schubert, et al. Cancer Res (2023) 83 (7_Supplement): 2116.

BAY 2965501 (BAY2965501)

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BAY 2965501 (BAY2965501)

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