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首页-小分子抑制剂&激动剂-Others-Diacylglycerol Kinase (DGK)-BAY 2965501
BAY 2965501

Chemical Structure : BAY 2965501

CAS No.: 2732902-08-6

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BAY 2965501 (Veludacigib, BAY2965501)

货号: PC-20666Not For Human Use, Lab Use Only.

Veludacigib (BAY2965501) is a potent selective inhibitor of diacylglycerol kinases zeta (DGKζ), restores T-cell cellular DAG level and induces pERK activation in anergic T-cells via DGK inhibition to assist T-cell mediate tumor cell kill.

规格 价格 库存 数量
5 mg ￥1480 In stock
10 mg ￥2180 In stock
25 mg ￥3780 In stock
50 mg ￥5980 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Veludacigib (BAY2965501) is a potent selective inhibitor of diacylglycerol kinases zeta (DGKζ), restores T-cell cellular DAG level and induces pERK activation in anergic T-cells via DGK inhibition to assist T-cell mediate tumor cell kill.

物理化学性质&存储条件

分子量 414.46
分子式 C20H19FN4O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(R)-2-((4-amino-5-(4-methoxybenzoyl)thiazol-2-yl)(4-fluorophenyl)amino)propanamide

参考文献

1. Nicole Schubert, et al. Cancer Res (2023) 83 (7_Supplement): 2116.

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