BAY1830839 | IRAK4 inhibitor | Probechem Biochemicals

Chemical Structure : BAY1830839

CAS No.: 1931994-80-7

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货号: PC-38684Not For Human Use, Lab Use Only.

BAY1830839 is a potent, selective IRAK4 inhibitor with IC50 of 3.0 nM, inhibits IRAK4 mediated activation of the TLR/MYD88 pathway.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

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BAY1830839 is a potent, selective IRAK4 inhibitor with IC50 of 3.0 nM, inhibits IRAK4 mediated activation of the TLR/MYD88 pathway.

分子量	450.462
分子式	C22H25F3N4O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[2-(3-Hydroxy-3-methylbutyl)-6-(1-hydroxy-1-methylethyl)-2H-indazol-5-yl]-6-(trifluoromethyl)-2-pyridinecarboxamide

1. Michael D Wiese et al. Expert Opin Investig Drugs. 2020 May;29(5):475-482.

2. Zheng J, et al. Bioorg Med Chem Lett. 2021 Apr 15;38:127862.

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