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首页-小分子抑制剂&激动剂-GPCR-Prostaglandin Receptor-BAY1316957
BAY1316957

Chemical Structure : BAY1316957

CAS No.: 1613264-40-6

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BAY1316957 (BAY 1316957)

货号: PC-36057Not For Human Use, Lab Use Only.

BAY1316957 (BAY 1316957) is a highly potent, selective, orally available human prostaglandin E2 receptor subtype 4 (hEP4-R) antagonist with IC50 of 15.3 nM.

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5 mg ￥1380 In stock
10 mg ￥2180 In stock
25 mg ￥3880 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BAY1316957 (BAY 1316957) is a highly potent, selective, orally available human prostaglandin E2 receptor subtype 4 (hEP4-R) antagonist with IC50 of 15.3 nM.
BAY1316957 significantly reduced pain related paw withdrawal behavior in the rat upon mechanical stimulation of the dmPGE2 treated hind paw.

物理化学性质&存储条件

分子量 441.531
分子式 C27H27N3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
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Solubility

DMSO: 100 mg/mL
Chemical Name/SMILES

2-(9-Ethyl-6-methyl-9H-carbazol-3-yl)-1-(2-methoxyethyl)-4-methyl-1H-benzimidazole-5-carboxylic acid

参考文献

1. Bäurle S, et al. J Med Chem. 2019 Feb 1. doi: 10.1021/acs.jmedchem.8b01862.

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