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首页-小分子抑制剂&激动剂-GPCR-Luteinizing Hormone Receptor (LHR)-BAY-899
BAY-899

Chemical Structure : BAY-899

CAS No.: 2471967-92-5

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BAY-899 (BAY899)

货号: PC-72912Not For Human Use, Lab Use Only.

BAY-899 (BAY899) is a highly potent, selective luteinizing hormone receptor (LH-R) inhibitor with IC50 of 185 nM and 46 nM for hLH-R and rLH-R, respectively.

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10 mg ￥1580 In stock
25 mg ￥2580 In stock
50 mg ￥4280 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BAY-899 (BAY899) is a highly potent, selective luteinizing hormone receptor (LH-R) inhibitor with IC50 of 185 nM and 46 nM for hLH-R and rLH-R, respectively.
BAY-899 reduces sex hormone levels in vivo.
BAY-899 is a valuable tool compound to study hLH-R signaling in vitro and to interfere with the production of sex hormones in vivo.

物理化学性质&存储条件

分子量 459.457
分子式 C25H19F2N5O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(5S)-N-[2-(4-Fluorophenoxy)pyrimidin-5-yl]-5-(4-fluorophenyl)-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxamide

参考文献

1. Lars Wortmann, et al. J Med Chem. 2019 Nov 27;62(22):10321-10341.

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