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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Glucose Transporter (GLUT)-BAY-876
BAY-876

Chemical Structure : BAY-876

CAS No.: 1799753-84-6

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BAY-876 (BAY876)

货号: PC-42031Not For Human Use, Lab Use Only.

BAY-876 (BAY876) is a potent, highly selective and oral bioavailable GLUT1 inhibitor with IC50 of 2 nM.

规格 价格 库存 数量
5 mg ￥1180 In stock
10 mg ￥1880 In stock
25 mg ￥3280 In stock
50 mg ￥5280 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BAY-876 (BAY876) is a potent, highly selective and oral bioavailable GLUT1 inhibitor with IC50 of 2 nM.
BAY-876 displays >100-fold selectivity against GLUT2, GLUT3, and GLUT4.
BAY-876 exhibits good metabolic stability in vitro and high oral bioavailability in vivo.

物理化学性质&存储条件

分子量 496.4164
分子式 C24H16F4N6O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 100 mg/mL
Chemical Name/SMILES

2,4-Quinolinedicarboxamide, N4-[1-[(4-cyanophenyl)methyl]-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-7-fluoro-

参考文献

1. Siebeneicher H, et al. ChemMedChem. 2016 Oct 19;11(20):2261-2271.

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