Chemical Structure : BAY-678
CAS No.: 675103-36-3
货号: PC-60473Not For Human Use, Lab Use Only.
BAY-678 (BAY678) potent, selective, cell permeable human neutrophil elastase (HNE) inhibitor with IC50 of 20 nM.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | ¥1180 | In stock | |
25 mg | ¥1980 | In stock | |
50 mg | ¥3280 | In stock | |
100 mg | Get quote |
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BAY-678 (BAY678) potent, selective, cell permeable human neutrophil elastase (HNE) inhibitor with IC50 of 20 nM.
BAY-678 displays >2,000-fold selectivity over a panel of serine proteases (IC50>30 uM).
分子量 | 400.361 | |
分子式 | C20H15F3N4O2 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
5-[(4R)-5-acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile |
1. von Nussbaum F, et al. ChemMedChem. 2015 Jul;10(7):1163-73.
2. von Nussbaum F, et al. ChemMedChem. 2016 Jan 19;11(2):199-206.
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