BAY-598 |CAS:906919-67-2 Probechem Biochemicals

Chemical Structure : BAY-598

CAS No.: 906919-67-2

加入收藏

BAY-598 (BAY598;BAY 598)

货号: PC-60420Not For Human Use, Lab Use Only.

BAY-598 (BAY598) is a potent, selective, and cell-active, substrate-competitive inhibitor of SMYD2 with IC50 of 27±7 nM in the biochemical SPA assay.

规格	价格	库存
5 mg	￥1280	In stock
10 mg	￥1880	In stock
25 mg	￥2980	In stock
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

BAY-598 (BAY598) is a potent, selective, and cell-active, substrate-competitive inhibitor of SMYD2 with IC50 of 27±7 nM in the biochemical SPA assay.
BAY-598 displays >100-fold selectivity over other HMTases (SMYD3, SUV420H1, SUV420H2, etc.) and other non-epigenetic targets.
BAY-598 inhibits the methylation of p53K370 in cells with IC50 <1 uM, has properties that are compatible with in vivo experiments.

物理化学性质&存储条件

分子量	525.3
分子式	C22H20Cl2F2N6O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S,Z)-N-(1-(N'-cyano-N-(3-(difluoromethoxy)phenyl)carbamimidoyl)-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol-4-yl)-N-ethyl-2-hydroxyacetamide

参考文献

1. Eggert E, et al. J Med Chem. 2016 May 26;59(10):4578-600.

BAY-598 (BAY598;BAY 598)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

BAY-598 (BAY598;BAY 598)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.