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首页-小分子抑制剂&激动剂-Others-Other Targets-BAY-252
BAY-252

Chemical Structure : BAY-252

CAS No.: 2639638-67-6

BAY-252 (BAY252)

货号: PC-26616Not For Human Use, Lab Use Only.

BAY-252 is a potent branched-chain amino acid transaminases 1 (BCAT1) and BCAT2 inhibitor with IC50s of 2 μM and 2 μM, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

BAY-252 is a potent branched-chain amino acid transaminases 1 (BCAT1) and BCAT2 inhibitor with IC50s of 2 μM and 2 μM, respectively.

物理化学性质&存储条件

分子量 446.81
分子式 C22H14ClF3N2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(4-chloro-3-(o-tolyloxy)naphthalen-1-yl)-6-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione

参考文献

1. Judith Günther, et al. J Med Chem. 2022 Oct 19. doi: 10.1021/acs.jmedchem.2c00441.

2. Patent WO2021063821 A1.

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