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首页-小分子抑制剂&激动剂-Others-Other Targets-BACH2 inhibitor compound 8
BACH2 inhibitor compound 8

Chemical Structure : BACH2 inhibitor compound 8

CAS No.: 1325718-66-8

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BACH2 inhibitor compound 8

货号: PC-72817Not For Human Use, Lab Use Only.

BACH2 inhibitor compound 8 is a potent, dual BACH2/BACH1 inhibitor.

规格 价格 库存 数量
2 mg ￥2980 In stock
5 mg ￥4980 In stock
10 mg ￥7580 In stock
25 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BACH2 inhibitor compound 8 is a potent, dual BACH2/BACH1 inhibitor.
BACH inhibitor compound 8 lowered glycemia and increased plasma insulin levels in diabetic mice, and restored insulin secretion in diabetic mice and human islets.

物理化学性质&存储条件

分子量 465.451
分子式 C20H18F3N5O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-Methyl-2-(6-trifluoromethoxy-benzothiazol-2-ylamino)-1H-benzoimidazole-5-carboxylic acid (2-methoxy-ethyl)-amide

参考文献

1. Jinsook Son, et al. J Clin Invest. 2021 Dec 15;131(24):e153876.

2. Patent WO2012094580

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