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首页-小分子抑制剂&激动剂-Others-Other Targets-B0045
B0045

Chemical Structure : B0045

CAS No.: 518018-54-7

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B0045

货号: PC-26920Not For Human Use, Lab Use Only.

B0045 is a specific, second-generation inhibitor of DCAF1 (Vpr-binding protein, VprBP), blocks VprBP-mediated H2AT120p and reactivates growth regulatory genes, resulting in a significantly lower proliferative capacity of prostate cancer cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

B0045 is a specific, second-generation inhibitor of DCAF1 (Vpr-binding protein, VprBP), blocks VprBP-mediated H2AT120p and reactivates growth regulatory genes, resulting in a significantly lower proliferative capacity of prostate cancer cells.

物理化学性质&存储条件

分子量 380.85
分子式 C19H13ClN4OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-((2-(5-(4-chlorophenyl)thieno[2,3-d]pyrimidin-4-yl)hydrazineylidene)methyl)phenol

参考文献

1. Sungmin Kim, et al. Cell Commun Signal. 2026 May 26. doi: 10.1186/s12964-026-02956-3.

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