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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-IRE1-B-I09
B-I09

Chemical Structure : B-I09

CAS No.: 1607803-67-7

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B-I09 (B I09, BI 09)

货号: PC-47078Not For Human Use, Lab Use Only.

B-I09 is a cell permeable IRE-1 RNase inhibitor with IC50 of 1.23 uM, inhibits IRE-1/XBP1 pathway, inhibits growth of human chronic lymphocytic leukemia (CLL) cells both in vitro and in vivo.

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5 mg ￥1180 In stock
10 mg ￥1880 In stock
25 mg ￥2980 In stock
50 mg ￥4580 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

B-I09 is a cell permeable IRE-1 RNase inhibitor with IC50 of 1.23 uM, inhibits IRE-1/XBP1 pathway, inhibits growth of human chronic lymphocytic leukemia (CLL) cells both in vitro and in vivo.

物理化学性质&存储条件

分子量 303.31
分子式 C16H17NO5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

7-(1,3-Dioxan-2-yl)-1,2,3,4-tetrahydro-8-hydroxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one

参考文献

1. Chih-Hang Anthony Tang, et al. J Clin Invest. 2014 Jun;124(6):2585-98.

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